SLC8A3 Antibody

Product Specifications

Background

This gene encodes a member of the sodium/calcium exchanger integral membrane protein family. Three mammalian isoforms in family 8 have been identified. Na+/Ca2+ exchange proteins are involved in maintaining Ca2+ homeostasis in a wide variety of cell types. The protein is regulated by intracellular calcium ions and is found in both the plasma membrane and intracellular organellar membranes, where exchange of Na+ for Ca2+ occurs in an electrogenic manner. Alternative splicing has been observed for this gene and multiple variants have been described.

NCBI Gene ID

6547

Swiss Prot

P57103

Accession Number

P57103

Host

Rabbit

Reactivity

Human

Immunogen

This SLC8A3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 585-614 amino acids from the C-terminal region of human SLC8A3.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Signal Transduction

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

103 kDa

Fragment

Rabbit Ig

Symbol

SLC8A3

NCBI Official Name

Sodium/calcium exchanger 3

NCBI Organism

Homo sapiens

Background Reference 01

Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :

Background Reference 02

Pulina, M.V., et al. J. Biol. Chem. 281 (28) :19645-19654 (2006)

Background Reference 03

Gomez-Villafuertes, R., et al. J. Neurosci. 25 (47) :10822-10830 (2005)

Background Reference 04

Lindgren, R.M., et al. Gene 348, 143-155 (2005) :

Other Product Names

Sodium/calcium exchanger 3, Na (+) /Ca (2+) -exchange protein 3, Solute carrier family 8 member 3, SLC8A3, NCX3

Tested Applications

WB, IHC-P

Protein ID

34395973

Physical Properties

Liquid

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