MCF2 Antibody

Product Specifications

Background

The oncogenic protein encoded by this gene is a guanine nucleotide exchange factor (GEF) that exerts control over some members of the Rho family of small GTPases. Several transcript variants encoding different isoforms have been found for this gene. These isoforms exhibit different expression patterns and varying levels of GEF activity.

NCBI Gene ID

4168

Swiss Prot

P10911

Accession Number

P10911

Host

Rabbit

Reactivity

Human

Immunogen

This MCF2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 804-833 amino acids from the C-terminal region of human MCF2.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cancer, Signal Transduction

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

108 kDa

Fragment

Rabbit Ig

Symbol

MCF2

NCBI Official Name

Proto-oncogene DBL

NCBI Organism

Homo sapiens

Background Reference 01

Piton, A., et al. Mol. Psychiatry (2010) In press :

Background Reference 02

Murakami, M., et al. Int. J. Cancer 123 (3) :500-510 (2008)

Background Reference 03

Murakami, M., et al. Cancer Biol. Ther. 7 (5) :677-688 (2008)

Background Reference 04

Rojas, R.J., et al. J. Biol. Chem. 282 (40) :29201-29210 (2007)

Other Product Names

Proto-oncogene DBL, Proto-oncogene MCF-2, MCF2-transforming protein, DBL-transforming protein, MCF2, DBL

Tested Applications

WB, IHC-P, Flow

Protein ID

92087039

Physical Properties

Liquid

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