MAN2A2 Antibody

Product Specifications

Background

MAN2A2 catalyzes the first committed step in the biosynthesis of complex N-glycans. It controls conversion of high mannose to complex N-glycans; the final hydrolytic step in the N-glycan maturation pathway.

NCBI Gene ID

4122

Swiss Prot

P49641

Accession Number

P49641

Host

Rabbit

Reactivity

Human, Mouse

Immunogen

This MAN2A2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 767-796 amino acids from the Central region of human MAN2A2.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Signal Transduction

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

131 kDa

Fragment

Rabbit Ig

Symbol

MAN2A2

NCBI Official Name

Alpha-mannosidase 2x

NCBI Organism

Homo sapiens

Background Reference 01

Lesch, K.P., et al.Neural Transm 115 (11) :1573-1585 (2008)

Background Reference 02

Stelzl, U., et al. Cell 122 (6) :957-968 (2005)

Background Reference 03

Hillman, R.T., et al. Genome Biol. (2), R8 (2004) :

Background Reference 04

Misago, M., et al. Proc. Natl. Acad. Sci. U.S.A. 92 (25) :11766-11770 (1995)

Other Product Names

Alpha-mannosidase 2x, Alpha-mannosidase IIx, Man IIx, Mannosidase alpha class 2A member 2, Mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase, MAN2A2, MANA2X