CCT8 Antibody

Product Specifications

Background

Molecular chaperone; CCT8 assists the folding of proteins upon ATP hydrolysis. As part of the BBS/CCT complex may play a role in the assembly of BBSome, a complex involved in ciliogenesis regulating transports vesicles to the cilia. Known to play a role, in vitro, in the folding of actin and tubulin.

NCBI Gene ID

10694

Swiss Prot

P50990

Accession Number

P50990

Host

Rabbit

Reactivity

Human

Immunogen

This CCT8 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 519-548 amino acids from the C-terminal region of human CCT8.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Signal Transduction

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Homology

Predicted species reactivity based on immunogen sequence: Monkey, Mouse

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

60 kDa

Fragment

Rabbit Ig

Symbol

CCT8

NCBI Official Name

T-complex protein 1 subunit theta

NCBI Organism

Homo sapiens

Background Reference 01

Mukherjee, K., et al. BMC Evol. Biol. 10, 64 (2010) :

Background Reference 02

Zebol, J.R., et al. Int. J. Biochem. Cell Biol. 41 (4) :822-827 (2009)

Background Reference 03

Kim, S.C., et al. Mol. Cell 23 (4) :607-618 (2006)

Background Reference 04

Hu, Y.H., et al. BMC Genomics 7, 155 (2006) :

Other Product Names

T-complex protein 1 subunit theta, TCP-1-theta, CCT-theta, Renal carcinoma antigen NY-REN-15, CCT8, C21orf112, CCTQ, KIAA0002

Tested Applications

WB, IHC-P, Flow

Protein ID

9988062

Physical Properties

Liquid

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