DNAJB6 Antibody

Product Specifications

Background

This gene encodes a member of the DNAJ protein family. DNAJ family members are characterized by a highly conserved amino acid stretch called the 'J-domain' and function as one of the two major classes of molecular chaperones involved in a wide range of cellular events, such as protein folding and oligomeric protein complex assembly. This family member may also play a role in polyglutamine aggregation in specific neurons. Alternative splicing of this gene results in multiple transcript variants; however, not all variants have been fully described.

NCBI Gene ID

10049

Swiss Prot

O75190

Accession Number

O75190

Host

Rabbit

Reactivity

Human

Immunogen

This DNAJB6 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 218-247 amino acids from the Central region of human DNAJB6.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Neuroscience, Signal Transduction

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

36 kDa

Fragment

Rabbit Ig

Symbol

DNAJB6

NCBI Official Name

DnaJ homolog subfamily B member 6

NCBI Organism

Homo sapiens

Background Reference 01

Mitra, A., et al. J. Biol. Chem. 285 (32) :24686-24694 (2010)

Background Reference 02

Edo De Bock, C., et al. Int. J. Oncol. 36 (5) :1155-1163 (2010)

Background Reference 03

Hageman, J., et al. Mol. Cell 37 (3) :355-369 (2010)

Background Reference 04

Lowe, J.K., et al. PLoS Genet. (2), E1000365 (2009) :

Other Product Names

DnaJ homolog subfamily B member 6, HHDJ1, Heat shock protein J2, HSJ-2, MRJ, MSJ-1, DNAJB6, HSJ2, MRJ, MSJ1

Tested Applications

WB, IHC-P, Flow

Physical Properties

Liquid

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