IL6 Antibody

Product Specifications

Background

This gene encodes a cytokine that functions in inflammation and the maturation of B cells. The protein is primarily produced at sites of acute and chronic inflammation, where it is secreted into the serum and induces a transcriptional inflammatory response through interleukin 6 receptor, alpha. The functioning of this gene is implicated in a wide variety of inflammation-associated disease states, including suspectibility to diabetes mellitus and systemic juvenile rheumatoid arthritis.

NCBI Gene ID

3569

Swiss Prot

P05231

Accession Number

P05231

Host

Rabbit

Reactivity

Human

Immunogen

This IL6 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 27-55 amino acids from the Central region of human IL6.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cancer, Immunology, Obesity, Neuroscience, Signal Transduction

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

24 kDa

Fragment

Rabbit Ig

Symbol

IL6

NCBI Official Name

Interleukin-6

NCBI Organism

Homo sapiens

Background Reference 01

Perez, A.B., et al. Hum. Immunol. 71 (11) :1135-1140 (2010)

Background Reference 02

Weng, X.M., et al. Zhonghua Shi Yan He Lin Chuang Bing Du Xue Za Zhi 24 (1) :42-44 (2010)

Background Reference 03

Santhosh, S., et al. Trop Gastroenterol 31 (1) :30-33 (2010)

Background Reference 04

Gein, O.N., et al. Patol Fiziol Eksp Ter 1, 10-13 (2010) :

Other Product Names

Interleukin-6, IL-6, B-cell stimulatory factor 2, BSF-2, CTL differentiation factor, CDF, Hybridoma growth factor, Interferon beta-2, IFN-beta-2, IL6, IFNB2