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RNF5 Antibody

Product Specifications

Background

The protein encoded by this gene contains a RING finger, which is a motif known to be involved in protein-protein interactions. This protein is a membrane-bound ubiquitin ligase. It can regulate cell motility by targeting paxillin ubiquitination and altering the distribution and localization of paxillin in cytoplasm and cell focal adhesions.

NCBI Gene ID

6048

Swiss Prot

Q99942

Accession Number

Q99942

Host

Rabbit

Reactivity

Human

Immunogen

This RNF5 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 65-94 amino acids from the Central region of human RNF5.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cancer, Cell Cycle, Immunology

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Homology

Predicted species reactivity based on immunogen sequence: Mouse, Rat

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

20 kDa

Fragment

Rabbit Ig

Symbol

RNF5

NCBI Official Name

E3 ubiquitin-protein ligase RNF5

NCBI Organism

Homo sapiens

Background Reference 01

Barcellos, L.F., et al. PLoS Genet. (10), E1000696 (2009) :

Background Reference 02

Tcherpakov, M., et al. J. Biol. Chem. 284 (18) :12099-12109 (2009)

Background Reference 03

Zhong, B., et al. Immunity 30 (3) :397-407 (2009)

Background Reference 04

McKinnon, E., et al. Diabetes Obes Metab 11 SUPPL 1, 92-100 (2009) :

Other Product Names

E3 ubiquitin-protein ligase RNF5, 632-, Protein G16, RING finger protein 5, Ram1 homolog, HsRma1, RNF5, G16, NG2, RMA1

Tested Applications

WB, IHC-P

Protein ID

74762702

Physical Properties

Liquid

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