SENP2 Antibody

Product Specifications

Background

SUMO is a small ubiquitin-like protein that can be covalently conjugated to other proteins. SENP2 is one of a group of enzymes that process newly synthesized SUMO1, SUMO2, and SUMO3 into the conjugatable mature forms and catalyze the deconjugation of these same SUMO proteins from their targeted substrates. SENP2 may also down-regulate CTNNB1 levels and thereby modulate the Wnt pathway.

NCBI Gene ID

59343

Swiss Prot

Q9HC62

Accession Number

Q9HC62

Host

Rabbit

Reactivity

Human, Mouse

Immunogen

This SENP2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 502-533 amino acids from the C-terminal region of human SENP2.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cell Cycle

Purification

This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

68 kDa

Fragment

Rabbit Ig

Symbol

SENP2

NCBI Official Name

Sentrin-specific protease 2

NCBI Organism

Homo sapiens

Background Reference 01

Ota, T., et al., Nat. Genet. 36 (1) :40-45 (2004) .

Background Reference 02

Nakajima, D., et al., DNA Res. 9 (3) :99-106 (2002) .

Background Reference 03

Zhang, H., et al., Mol. Cell. Biol. 22 (18) :6498-6508 (2002) .

Background Reference 04

Hang, J., et al., J. Biol. Chem. 277 (22) :19961-19966 (2002) .

Other Product Names

Sentrin-specific protease 2, Axam2, SMT3-specific isopeptidase 2, Smt3ip2, Sentrin/SUMO-specific protease SENP2, SENP2, KIAA1331

Tested Applications

WB, IHC-P

Protein ID

143811458

Physical Properties

Liquid

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