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TLE2 Antibody

Product Specifications

Background

TLE2 is a transcriptional corepressor that binds to a number of transcription factors. Inhibits the transcriptional activation mediated by CTNNB1 and TCF family members in Wnt signaling. The effects of full-length TLE family members may be modulated by association with dominant-negative AES (By similarity) .

NCBI Gene ID

7089

Swiss Prot

Q04725

Accession Number

Q04725

Host

Rabbit

Reactivity

Mouse

Immunogen

This TLE2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 637-665 amino acids from the C-terminal region of human TLE2.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Other

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Product Datasheet

https://www.prosci-inc.com/?datasheet_sku=56-312

Calculated Molecular Weight

80 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

TLE2

NCBI Official Name

Transducin-like enhancer protein 2

NCBI Organism

Homo sapiens

Background Reference 01

He, Z., et al. J. Virol. 84 (4) :2047-2062 (2010)

Background Reference 02

Arce, L., et al. BMC Cancer 9, 159 (2009) :

Background Reference 03

Higa, L.A., et al. Nat. Cell Biol. 8 (11) :1277-1283 (2006)

Background Reference 04

Javed, A., et al. J. Cell. Sci. 113 (PT 12), 2221-2231 (2000) :

Other Product Names

Transducin-like enhancer protein 2, Enhancer of split groucho-like protein 2, ESG2, TLE2

Tested Applications

WB

Protein ID

20532416

Physical Properties

Liquid

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