INTS1 Antibody
Product Specifications
Background
INTS1 is a subunit of the Integrator complex, which associates with the C-terminal domain of RNA polymerase II large subunit (POLR2A; MIM 180660) and mediates 3-prime end processing of small nuclear RNAs U1 (RNU1; MIM 180680) and U2 (RNU2; MIM 180690) (Baillat et al., 2005 [PubMed 16239144]) .
NCBI Gene ID
26173
Swiss Prot
Q8N201
Accession Number
Q8N201
Host
Rabbit
Reactivity
Human
Immunogen
This INTS1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 113-142 amino acids from the N-terminal region of human INTS1.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Other
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Homology
Predicted species reactivity based on immunogen sequence: Mouse
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
244 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
INTS1
NCBI Official Name
Integrator complex subunit 1
NCBI Organism
Homo sapiens
Background Reference 01
Nusbaum, C., et al. Nature 439 (7074) :331-335 (2006)
Background Reference 02
Baillat, D., et al. Cell 123 (2) :265-276 (2005)
Background Reference 03
Clark, H.F., et al. Genome Res. 13 (10) :2265-2270 (2003)
Other Product Names
Integrator complex subunit 1, Int1, INTS1, KIAA1440
Tested Applications
WB
Protein ID
97052424
Physical Properties
Liquid
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