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STUB1 Antibody

Product Specifications

Background

STUB1, or CHIP, is a ubiquitin ligase/cochaperone that participates in protein quality control by targeting a broad range of chaperone protein substrates for degradation (Min et al., 2008 [PubMed 18411298]) .

NCBI Gene ID

10273

Swiss Prot

Q9UNE7

Accession Number

Q9UNE7

Host

Rabbit

Reactivity

Human

Immunogen

This STUB1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 236-263 amino acids from the C-terminal region of human STUB1.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Signal Transduction

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Homology

Predicted species reactivity based on immunogen sequence: Chicken, Mouse

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

35 kDa

Fragment

Rabbit Ig

Symbol

STUB1

NCBI Official Name

E3 ubiquitin-protein ligase CHIP

NCBI Organism

Homo sapiens

Background Reference 01

Stankiewicz, M., et al. FEBS J. 277 (16) :3353-3367 (2010)

Background Reference 02

Naito, A.T., et al. Circ. Res. 106 (11) :1692-1702 (2010)

Background Reference 03

Loffek, S., et al. Hum. Mutat. 31 (4) :466-476 (2010)

Background Reference 04

Graf, C., et al. Biochemistry 49 (10) :2121-2129 (2010)

Other Product Names

HGNC:11427

Tested Applications

WB, Flow

Protein ID

78099173

Physical Properties

Liquid

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