MDK Antibody

Product Specifications

Background

Midkine is a retinoic acid-responsive, heparin-binding growth factor expressed in various cell types during embryogenesis. It promotes angiogenesis, cell growth, and cell migration. Midkine is also expressed in several carcinomas, suggesting that it may play a role in tumorigenesis, perhaps through its effects on angiogenesis (summary by Reynolds et al., 2004 [PubMed 15197188]) .

NCBI Gene ID

4192

Swiss Prot

P21741

Accession Number

P21741

Host

Rabbit

Reactivity

Human, Mouse

Immunogen

This MDK antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 113-143 amino acids from the C-terminal region of human MDK.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Neuroscience

Purification

This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

16 kDa

Fragment

Rabbit Ig

Symbol

MDK

NCBI Official Name

Midkine

NCBI Organism

Homo sapiens

Background Reference 01

Ferreira, R.C., et al. Nat. Genet. 42 (9) :777-780 (2010) Kerzerho, J., et al. J. Immunol. 185 (1) :418-423 (2010) Yao, X., et al. Acta Pharmacol. Sin. 31 (5) :629-637 (2010) Zhang, Z.H., et al. Cell Prolif. 43 (2) :184-194 (2010) Rice, G.E., et al. J. Exp. Clin. Cancer Res. 29, 62 (2010) :

Other Product Names

Midkine, MK, Amphiregulin-associated protein, ARAP, Midgestation and kidney protein, Neurite outgrowth-promoting factor 2, Neurite outgrowth-promoting protein, MDK, MK1, NEGF2