TBCA Antibody
Product Specifications
Background
The product of this gene is one of four proteins (cofactors A, D, E, and C) involved in the pathway leading to correctly folded beta-tubulin from folding intermediates. Cofactors A and D are believed to play a role in capturing and stabilizing beta-tubulin intermediates in a quasi-native confirmation. Cofactor E binds to the cofactor D/beta-tubulin complex; interaction with cofactor C then causes the release of beta-tubulin polypeptides that are committed to the native state. This gene encodes chaperonin cofactor A.
NCBI Gene ID
6902
Swiss Prot
O75347
Accession Number
O75347
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
This TBCA antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 30-58 amino acids from the Central region of human TBCA.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Signal Transduction
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
13 kDa
Fragment
Rabbit Ig
Symbol
TBCA
NCBI Official Name
Tubulin-specific chaperone A
NCBI Organism
Homo sapiens
Background Reference 01
Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :
Background Reference 02
Joslyn, G., et al. Alcohol. Clin. Exp. Res. 34 (5) :800-812 (2010)
Background Reference 03
Bruneel, A., et al. Proteomics 5 (15) :3876-3884 (2005)
Background Reference 04
Nolasco, S., et al. FEBS Lett. 579 (17) :3515-3524 (2005)
Other Product Names
Tubulin-specific chaperone A, TCP1-chaperonin cofactor A, Tubulin-folding cofactor A, CFA, TBCA
Tested Applications
WB, IHC-P
Physical Properties
Liquid
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