PCDH1 Antibody

Product Specifications

Background

This gene belongs to the protocadherin subfamily within the cadherin superfamily. The encoded protein is a membrane protein found at cell-cell boundaries. It is involved in neural cell adhesion, suggesting a possible role in neuronal development. The protein includes an extracelllular region, containing 7 cadherin-like domains, a transmembrane region and a C-terminal cytoplasmic region. Cells expressing the protein showed cell aggregation activity. Alternative splicing occurs in this gene.

NCBI Gene ID

5097

Swiss Prot

Q08174

Accession Number

Q08174

Host

Rabbit

Reactivity

Human

Immunogen

This PCDH1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 179-206 amino acids from the N-terminal region of human PCDH1.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Neuroscience, Signal Transduction

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

115 kDa

Fragment

Rabbit Ig

Symbol

PCDH1

NCBI Official Name

Protocadherin-1

NCBI Organism

Homo sapiens

Background Reference 01

Koppelman, G.H., et al. Am. J. Respir. Crit. Care Med. 180 (10) :929-935 (2009)

Background Reference 02

Rush, J., et al. Nat. Biotechnol. 23 (1) :94-101 (2005)

Background Reference 03

Ballif, B.A., et al. Mol. Cell Proteomics 3 (11) :1093-1101 (2004)

Background Reference 04

Ballif, B.A., et al. Mol. Cell Proteomics 3 (11) :1093-1101 (2004)

Other Product Names

Protocadherin-1, Cadherin-like protein 1, Protocadherin-42, PC42, PCDH1

Tested Applications

WB, IHC-P, IF

Protein ID

215273864

Physical Properties

Liquid

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