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EIF5AL1 Antibody

Product Specifications

Background

EIF5AL1is a mRNA-binding protein involved in translation elongation. Has an important function at the level of mRNA turnover, probably acting downstream of decapping. Involved in actin dynamics and cell cycle progression, mRNA decay and probably in a pathway involved in stress response and maintenance of cell wall integrity. Functions as a regulator of apoptosis. Mediates effects of polyamines on neuronal process extension and survival. May play an important role in brain development and function, and in skeletal muscle stem cell differentiation (By similarity) .

NCBI Gene ID

143244

Swiss Prot

Q6IS14

Accession Number

Q6IS14

Host

Rabbit

Reactivity

Human

Immunogen

This EIF5AL1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 94-122 amino acids from the C-terminal region of human EIF5AL1.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Other

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

17 kDa

Fragment

Rabbit Ig

Symbol

EIF5AL1

NCBI Official Name

Eukaryotic translation initiation factor 5A-1-like

NCBI Organism

Homo sapiens

Background Reference 01

Kim, S.C., et al. Mol. Cell 23 (4) :607-618 (2006)

Background Reference 02

Clement, P.M., et al. FEBS J. 273 (6) :1102-1114 (2006)

Background Reference 03

Facchiano, A.M., et al. Protein Eng. 14 (11) :881-890 (2001)

Background Reference 04

Lipowsky, G., et al. EMBO J. 19 (16) :4362-4371 (2000)

Other Product Names

Eukaryotic translation initiation factor 5A-1-like, eIF-5A-1-like, eIF-5A1-like, Eukaryotic initiation factor 5A isoform 1-like, EIF5AL1

Tested Applications

WB, IHC-P, IF

Protein ID

190359775

Physical Properties

Liquid

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