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PRSS3 Antibody

Product Specifications

Background

This gene encodes a trypsinogen, which is a member of the trypsin family of serine proteases. This enzyme is expressed in the brain and pancreas and is resistant to common trypsin inhibitors. It is active on peptide linkages involving the carboxyl group of lysine or arginine. This gene is localized to the locus of T cell receptor beta variable orphans on chromosome 9. Four transcript variants encoding different isoforms have been described for this gene.

NCBI Gene ID

5646

Swiss Prot

P35030

Accession Number

P35030

Host

Rabbit

Reactivity

Human

Immunogen

This PRSS3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 136-163 amino acids from the Central region of human PRSS3.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cancer, Cell Cycle, Signal Transduction

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

33 kDa

Fragment

Rabbit Ig

Symbol

PRSS3

NCBI Official Name

Trypsin-3

NCBI Organism

Homo sapiens

Background Reference 01

Jiang, G., et al. Gut 59 (11) :1535-1544 (2010)

Background Reference 02

Nakanishi, J., et al. J. Invest. Dermatol. 130 (4) :944-952 (2010)

Background Reference 03

Salameh, M.A., et al. J. Biol. Chem. 285 (3) :1939-1949 (2010)

Background Reference 04

Rosendahl, J., et al. Pancreatology 10 (2-3), 243-249 (2010) :

Other Product Names

Trypsin-3, Brain trypsinogen, Mesotrypsinogen, Serine protease 3, Serine protease 4, Trypsin III, Trypsin IV, PRSS3, PRSS4, TRY3, TRY4

Tested Applications

WB, IHC-P, Flow

Protein ID

209572698

Physical Properties

Liquid

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