COL8A2 Antibody
Product Specifications
Background
This gene encodes the alpha 2 chain of type VIII collagen. The protein is a major component of the basement membrane of the corneal endothelium and forms homo- or heterotrimers with alpha 1 (VIII) type collagens. Defects in this gene are associated with Fuchs endothelial corneal dystrophy and posterior polymorphous corneal dystrophy type 2.
NCBI Gene ID
1296
Swiss Prot
P25067
Accession Number
P25067
Host
Rabbit
Reactivity
Human
Immunogen
This COL8A2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 571-599 amino acids from the C-terminal region of human COL8A2.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Signal Transduction
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
67 kDa
Fragment
Rabbit Ig
Symbol
COL8A2
NCBI Official Name
Collagen alpha-2 (VIII) chain
NCBI Organism
Homo sapiens
Background Reference 01
Hemadevi, B., et al. BMC Ophthalmol 10, (2010) :
Background Reference 02
Afshari, N.A., et al. Invest. Ophthalmol. Vis. Sci. 50 (3) :1093-1097 (2009)
Background Reference 03
Liskova, P., et al. BrOphthalmol 91 (12) :1717-1718 (2007)
Background Reference 04
Aldave, A.J., et al. Cornea 26 (8) :963-965 (2007)
Other Product Names
Collagen alpha-2 (VIII) chain, Endothelial collagen, COL8A2
Tested Applications
WB, IHC-P, IF
Protein ID
45644957
Physical Properties
Liquid
Curated Selection
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