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ENos Antibody

Product Specifications

Background

Nitric oxide is a reactive free radical which acts as a biologic mediator in several processes, including neurotransmission and antimicrobial and antitumoral activities. Nitric oxide is synthesized from L-arginine by nitric oxide synthases. Variations in this gene are associated with susceptibility to coronary spasm. Multiple transcript variants encoding different isoforms have been found for this gene.

NCBI Gene ID

4846

Swiss Prot

P29474

Accession Number

P29474

Host

Rabbit

Reactivity

Human

Immunogen

This eNos antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1156-1183 amino acids from human eNos.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cancer, Cell Cycle, Obesity, Neuroscience

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Homology

Predicted species reactivity based on immunogen sequence: Bovine, Mouse, Pig, Rat

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

133 kDa

Fragment

Rabbit Ig

Symbol

NOS3

NCBI Official Name

Nitric oxide synthase, endothelial

NCBI Organism

Homo sapiens

Background Reference 01

Yanamandra, K., et al. Ophthalmic Genet. 31 (4) :173-177 (2010)

Background Reference 02

Bambha, K., et al. Mayo Clin. Proc. 85 (9) :814-820 (2010)

Background Reference 03

Shin, S.J., et al. Eur. J. Obstet. Gynecol. Reprod. Biol. 152 (1) :64-67 (2010)

Background Reference 04

Kim, S.M., et al. Kardiol Pol 68 (8) :920-926 (2010)

Other Product Names

Nitric oxide synthase, endothelial, Constitutive NOS, cNOS, EC-NOS, Endothelial NOS, eNOS, NOS type III, NOSIII, NOS3

Tested Applications

WB, IF, Flow

Protein ID

266648

Physical Properties

Liquid

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