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EFNB2 Antibody

Product Specifications

Background

This gene encodes a member of the ephrin (EPH) family. The ephrins and EPH-related receptors comprise the largest subfamily of receptor protein-tyrosine kinases and have been implicated in mediating developmental events, especially in the nervous system and in erythropoiesis. Based on their structures and sequence relationships, ephrins are divided into the ephrin-A (EFNA) class, which are anchored to the membrane by a glycosylphosphatidylinositol linkage, and the ephrin-B (EFNB) class, which are transmembrane proteins. This gene encodes an EFNB class ephrin which binds to the EPHB4 and EPHA3 receptors.

NCBI Gene ID

1948

Swiss Prot

P52799

Accession Number

P52799

Host

Rabbit

Reactivity

Human

Immunogen

This EFNB2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 157-186 amino acids from the Central region of human EFNB2.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cancer, Cell Cycle, Neuroscience

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

37 kDa

Fragment

Rabbit Ig

Symbol

EFNB2

NCBI Official Name

Ephrin-B2

NCBI Organism

Homo sapiens

Background Reference 01

Zhang, R., et al. Psychiatry Res 180 (1) :5-9 (2010)

Background Reference 02

Bochenek, M.L., et al. J. Cell. Sci. 123 (PT 8), 1235-1246 (2010) :

Background Reference 03

Nakada, M., et al. Int. J. Cancer 126 (5) :1155-1165 (2010)

Background Reference 04

Qin, H., et al. J. Biol. Chem. 285 (1) :644-654 (2010)

Other Product Names

Ephrin-B2, EPH-related receptor tyrosine kinase ligand 5, LERK-5, HTK ligand, HTK-L, EFNB2, EPLG5, HTKL, LERK5

Tested Applications

WB, IHC-P, IF

Protein ID

1706673

Physical Properties

Liquid

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