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Rad9 Antibody

Product Specifications

Background

This gene product is highly similar to Schizosaccharomyces pombe rad9, a cell cycle checkpoint protein required for cell cycle arrest and DNA damage repair in response to DNA damage. This protein is found to possess 3' to 5' exonuclease activity, which may contribute to its role in sensing and repairing DNA damage. It forms a checkpoint protein complex with RAD1 and HUS1. This complex is recruited by checkpoint protein RAD17 to the sites of DNA damage, which is thought to be important for triggering the checkpoint-signaling cascade. Use of alternative polyA sites has been noted for this gene.

NCBI Gene ID

5883

Swiss Prot

Q99638

Accession Number

Q99638

Host

Rabbit

Reactivity

Human

Immunogen

This Rad9 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 365-391 amino acids from human Rad9.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Other

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Homology

Predicted species reactivity based on immunogen sequence: Monkey

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Product Datasheet

https://www.prosci-inc.com/?datasheet_sku=55-891

Calculated Molecular Weight

43 kDa

Fragment

Rabbit Ig

Symbol

RAD9A

NCBI Official Name

Cell cycle checkpoint control protein RAD9A

NCBI Organism

Homo sapiens

Background Reference 01

Bailey, S.D., et al. Diabetes Care 33 (10) :2250-2253 (2010)

Background Reference 02

Takeishi, Y., et al. Genes Cells 15 (7) :761-771 (2010)

Background Reference 03

Greer Card, D.A., et al. J. Biol. Chem. 285 (20) :15653-15661 (2010)

Background Reference 04

Bai, H., et al. DNA Repair (Amst.) 9 (5) :478-487 (2010)

Other Product Names

Cell cycle checkpoint control protein RAD9A, hRAD9, DNA repair exonuclease rad9 homolog A, RAD9A

Tested Applications

WB, IHC-P, IF

Protein ID

74717382

Physical Properties

Liquid

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