CPM Antibody

Product Specifications

Background

The protein encoded by this gene is a membrane-bound arginine/lysine carboxypeptidase. Its expression is associated with monocyte to macrophage differentiation. This encoded protein contains hydrophobic regions at the amino and carboxy termini and has 6 potential asparagine-linked glycosylation sites. The active site residues of carboxypeptidases A and B are conserved in this protein. Three alternatively spliced transcript variants encoding the same protein have been described for this gene. [provided by RefSeq].

NCBI Gene ID

1368

Swiss Prot

P14384

Accession Number

P14384

Host

Rabbit

Reactivity

Human

Immunogen

This CPM antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 212-241 amino acids from the Central region of human CPM.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Immunology, Signal Transduction

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

51 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

CPM

NCBI Official Name

Carboxypeptidase M

NCBI Organism

Homo sapiens

Background Reference 01

Rietschel, M., et al. Biol. Psychiatry 68 (6) :578-585 (2010) Erickson-Johnson, M.R., et al. Mod. Pathol. 22 (12) :1541-1547 (2009) Marquez-Curtis, L., et al. Stem Cells 26 (5) :1211-1220 (2008) Zhang, X., et al. J. Biol. Chem. 283 (12) :7994-8004 (2008) Elortza, F., et al. J. Proteome Res. 5 (4) :935-943 (2006)