COL4A2 Antibody

Product Specifications

Background

This gene encodes one of the six subunits of type IV collagen, the major structural component of basement membranes. The C-terminal portion of the protein, known as canstatin, is an inhibitor of angiogenesis and tumor growth. Like the other members of the type IV collagen gene family, this gene is organized in a head-to-head conformation with another type IV collagen gene so that each gene pair shares a common promoter.

NCBI Gene ID

1284

Swiss Prot

P08572

Accession Number

P08572

Host

Rabbit

Reactivity

Human

Immunogen

This COL4A2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 156-186 amino acids from the N-terminal region of human COL4A2.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cancer, Signal Transduction

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

168 kDa

Fragment

Rabbit Ig

Symbol

COL4A2

NCBI Official Name

Collagen alpha-2 (IV) chain

NCBI Organism

Homo sapiens

Background Reference 01

Bianchini, G., et al. J. Clin. Oncol. 28 (28) :4316-4323 (2010)

Background Reference 02

Romero, R., et al. Am. J. Obstet. Gynecol. 203 (4), 361 (2010) :

Background Reference 03

Bailey, S.D., et al. Diabetes Care 33 (10) :2250-2253 (2010)

Background Reference 04

Romero, R., et al. Am. J. Obstet. Gynecol. 202 (5), 431 (2010) :

Other Product Names

Collagen alpha-2 (IV) chain, Canstatin, COL4A2

Tested Applications

WB, Flow

Protein ID

143811377

Physical Properties

Liquid

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