Welcome to GenPrice! Check out our latest updates.

Shopping Cart (0)

Your cart is empty

Add some products to get started!

SP1 Antibody

Product Specifications

Background

Transcription factor that can activate or repress transcription in response to physiological and pathological stimuli. Binds with high affinity to GC-rich motifs and regulates the expression of a large number of genes involved in a variety of processes such as cell growth, apoptosis, differentiation and immune responses. Highly regulated by post-translational modifications (phosphorylations, sumoylation, proteolytic cleavage, glycosylation and acetylation) . Binds also the PDGFR-alpha G-box promoter. May have a role in modulating the cellular response to DNA damage. Implicated in chromatin remodeling. Plays a role in the recruitment of SMARCA4/BRG1 on the c-FOS promoter. Plays an essential role in the regulation of FE65 gene expression.

NCBI Gene ID

6667

Swiss Prot

P08047

Accession Number

P08047

Host

Rabbit

Reactivity

Human

Immunogen

This SP1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 677-707 amino acids from the C-terminal region of human SP1.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Obesity, Signal Transduction

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Homology

Predicted species reactivity based on immunogen sequence: Mouse, Rat

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Product Datasheet

https://www.prosci-inc.com/?datasheet_sku=55-854

Calculated Molecular Weight

81 kDa

Fragment

Rabbit Ig

Symbol

SP1

NCBI Official Name

Transcription factor Sp1

NCBI Organism

Homo sapiens

Background Reference 01

Pan, Q., et al. Biochem. Biophys. Res. Commun. 401 (2) :306-312 (2010)

Background Reference 02

Mucha, M., et al. J. Neurosci. 30 (40) :13235-13245 (2010)

Background Reference 03

Imanishi, M., et al. Biochem. Biophys. Res. Commun. 400 (4) :625-630 (2010)

Background Reference 04

Jutooru, I., et al. J. Biol. Chem. 285 (33) :25332-25344 (2010)

Other Product Names

Transcription factor Sp1, SP1, TSFP1

Tested Applications

WB, IHC-P, IF, Flow

Protein ID

13638437

Physical Properties

Liquid

Curated Selection

Explore Other Products

Discover premium biology products from our extensive collection of 20M+ items

Livin Polyclonal Antibody, Cy5 Conjugated
bs-20731R-Cy5 100 µL

Livin Polyclonal Antibody, Cy5 Conjugated

Ask
View Details
PIP5K Antibody (Phospho-Ser307) : Biotin (OAAF07642-Biotin)
OAAF07642-100UG-Biotin 100 µg

PIP5K Antibody (Phospho-Ser307) : Biotin (OAAF07642-Biotin)

Ask
View Details
BEX2 CRISPRa sgRNA lentivector (set of three targets)(Mouse)
13298124 3 x 1.0μg DNA

BEX2 CRISPRa sgRNA lentivector (set of three targets)(Mouse)

Ask
View Details
Recombinant SARS-CoV-2 (2019-nCoV) S Protein RBD (E484Q, L452R)
MBS1560499 Inquire

Recombinant SARS-CoV-2 (2019-nCoV) S Protein RBD (E484Q, L452R)

Ask
View Details
6-Amino-2-chloro-5-nitropyridine
MBS6097978-01 2.5 g

6-Amino-2-chloro-5-nitropyridine

Ask
View Details
6-Amino-2-chloro-5-nitropyridine
MBS6097978-02 5x 2.5 g

6-Amino-2-chloro-5-nitropyridine

Ask
View Details