DPP3 Antibody

Product Specifications

Background

This gene encodes a protein that is a member of the M49 family of metallopeptidases. This cytoplasmic protein binds a single zinc ion with its zinc-binding motif (HELLGH) and has post-proline dipeptidyl aminopeptidase activity, cleaving Xaa-Pro dipeptides from the N-termini of proteins. Increased activity of this protein is associated with endometrial and ovarian cancers. Alternate transcriptional splice variants have been characterized.

NCBI Gene ID

10072

Swiss Prot

Q9NY33

Accession Number

Q9NY33

Host

Rabbit

Reactivity

Human

Immunogen

This DPP3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 583-612 amino acids from the C-terminal region of human DPP3.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cell Cycle

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Homology

Predicted species reactivity based on immunogen sequence: Mouse

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

83 kDa

Fragment

Rabbit Ig

Symbol

DPP3

NCBI Official Name

Dipeptidyl peptidase 3

NCBI Organism

Homo sapiens

Background Reference 01

Shukla, A.A., et al. FEBS J. 277 (8) :1861-1875 (2010)

Background Reference 02

Salopek-Sondi, B., et al. Biol. Chem. 389 (2) :163-167 (2008)

Background Reference 03

Gevaert, K., et al. Proteomics 5 (14) :3589-3599 (2005)

Background Reference 04

Abramic, M., et al. Int. J. Biochem. Cell Biol. 36 (3) :434-446 (2004)

Other Product Names

Dipeptidyl peptidase 3, Dipeptidyl aminopeptidase III, Dipeptidyl arylamidase III, Dipeptidyl peptidase III, DPP III, Enkephalinase B, DPP3

Tested Applications

WB, IHC-P, IF, Flow

Protein ID

20532389

Physical Properties

Liquid

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