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EIF2B4 Antibody

Product Specifications

Background

Eukaryotic initiation factor 2B (EIF2B), which is necessary for protein synthesis, is a GTP exchange factor composed of five different subunits. The protein encoded by this gene is the fourth, or delta, subunit. Defects in this gene are a cause of leukoencephalopathy with vanishing white matter (VWM) and ovarioleukodystrophy. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq].

NCBI Gene ID

8890

Swiss Prot

Q9UI10

Accession Number

Q9UI10

Host

Rabbit

Reactivity

Human, Mouse

Immunogen

This EIF2B4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 146-175 amino acids from the Central region of human EIF2B4.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Other

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Homology

Predicted species reactivity based on immunogen sequence: Bovine

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

58 kDa

Fragment

Rabbit Ig

Symbol

EIF2B4

NCBI Official Name

Translation initiation factor eIF-2B subunit delta

NCBI Organism

Homo sapiens

Background Reference 01

Naukkarinen, J., et al. PLoS Genet. (6), E1000976 (2010) :

Background Reference 02

Wu, Y., et al. J. Hum. Genet. 54 (2) :74-77 (2009)

Background Reference 03

Horzinski, L., et al. PLoS ONE (12), E8318 (2009) :

Background Reference 04

Pronk, J., et al. Mult. Scler. 14 (8) :1123-1126 (2008)

Other Product Names

Translation initiation factor eIF-2B subunit delta, eIF-2B GDP-GTP exchange factor subunit delta, EIF2B4, EIF2BD

Tested Applications

WB, IHC-P

Protein ID

28381357

Physical Properties

Liquid

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