IGF2 Antibody

Product Specifications

Background

This gene encodes a member of the insulin family of polypeptide growth factors, which are involved in development and growth. It is an imprinted gene, expressed only from the paternal allele, and epigenetic changes at this locus are associated with Wilms tumour, Beckwith-Wiedemann syndrome, rhabdomyosarcoma, and Silver-Russell syndrome. A read-through INS-IGF2 gene exists, whose 5' region overlaps the INS gene and the 3' region overlaps this gene. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

NCBI Gene ID

3481

Swiss Prot

P01344

Accession Number

P01344

Host

Rabbit

Reactivity

Human, Mouse

Immunogen

This IGF2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 39-68 amino acids from the Central region of human IGF2.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cancer, Cell Cycle, Signal Transduction

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

20 kDa

Fragment

Rabbit Ig

Symbol

IGF2

NCBI Official Name

Insulin-like growth factor II

NCBI Organism

Homo sapiens

Background Reference 01

Adkins, R.M., et al. Pediatr. Res. 68 (5) :429-434 (2010)

Background Reference 02

Romero, R., et al. Am. J. Obstet. Gynecol. 203 (4), 361 (2010) :

Background Reference 03

Li, J., et al. Mol. Biol. Rep. (2010) In press :

Background Reference 04

Hsieh, Y.Y., et al. Anticancer Res. 30 (6) :2203-2208 (2010)

Other Product Names

Insulin-like growth factor II, IGF-II, Somatomedin-A, Insulin-like growth factor II, Insulin-like growth factor II Ala-25 Del, Preptin, IGF2

Tested Applications

WB, IHC-P, Flow

Protein ID

124255

Physical Properties

Liquid

Curated Selection

Explore Other Products

Discover premium biology products from our extensive collection of 20M+ items

RR212316L4 10 µg

Ube2m (NM_001108471) Rat Tagged Lenti ORF Clone

Ask

View Details

38355066 1.0 µg DNA

RAB5B Lentiviral Vector (Rat) (CMV) (pLenti-GIII-CMV)

Ask

View Details

NBP2-99343B 0.1 mL

Rabbit Polyclonal FXR1 Antibody [Biotin]

Ask

View Details

MBS6196547-01 0.1 mL

LRRN1 (Leucine Rich Repeat Neuronal 1, FIGLER3, KIAA1497, NLRR-1, LRCH4) (MaxLight 405)

Ask

View Details

MBS6196547-02 5x 0.1 mL

LRRN1 (Leucine Rich Repeat Neuronal 1, FIGLER3, KIAA1497, NLRR-1, LRCH4) (MaxLight 405)

Ask

View Details