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CCNB1 Antibody

Product Specifications

Background

The protein encoded by this gene is a regulatory protein involved in mitosis. The gene product complexes with p34 (cdc2) to form the maturation-promoting factor (MPF) . Two alternative transcripts have been found, a constitutively expressed transcript and a cell cycle-regulated transcript, that is expressed predominantly during G2/M phase. The different transcripts result from the use of alternate transcription initiation sites. [provided by RefSeq].

NCBI Gene ID

891

Swiss Prot

P14635

Accession Number

P14635

Host

Rabbit

Reactivity

Human

Immunogen

This CCNB1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 381-411 amino acids from the C-terminal region of human CCNB1.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cancer, Cell Cycle

Purification

This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

48 kDa

Fragment

Rabbit Ig

Symbol

CCNB1

NCBI Official Name

G2/mitotic-specific cyclin-B1

NCBI Organism

Homo sapiens

Background Reference 01

Kreis, N.N., et al. Oncogene 29 (41) :5591-5603 (2010)

Background Reference 02

Van Zon, W., et al. J. Cell Biol. 190 (4) :587-602 (2010)

Background Reference 03

Harley, M.E., et al. EMBO J. 29 (14) :2407-2420 (2010)

Background Reference 04

Olson, J.E., et al. Breast Cancer Res. Treat. (2010) In press :

Other Product Names

G2/mitotic-specific cyclin-B1, CCNB1, CCNB

Tested Applications

WB, IHC-P

Protein ID

116176

Physical Properties

Liquid

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