MAPK Antibody

Product Specifications

Background

Extracellular-Signal Regulated Kinase/Mitogen-Activated Protein Kinase (ERK/MAPK) is an integral component of cellular signaling during mitogenesis and differentiation of mitotic cells and also is thought to play a key role in learning and memory (Adams and Sweatt, 2002; Ahn, 1993; Tanoue and Nishida, 2003; Johnson and Lapadat, 2002) . The activity of this kinase is regulated by dual phosphorylation at Thr202 and Tyr204 (Ahn, 1993) .

NCBI Gene ID

116590

Swiss Prot

P63086

Accession Number

P63086

Host

Rabbit

Reactivity

Mouse, Rat

Immunogen

Peptide corresponding to amino acid residues from the C-terminus of rat ERK/MAPK.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Signal Transduction

Purification

Affinity Purified

Concentration

Batch dependent

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

MAPK antibody can be stored at -20˚ C and is stable at -20˚ C for at least 1 year.

Calculated Molecular Weight

42/44

Applications Notes

The antibody has been directly tested for reactivity in Western blots with rat tissue. It is anticipated that the antibody will also react with mouse tissue based on the fact that this species has 100% homology with the amino acid sequence used as antigen.