LASS1 Antibody

Product Specifications

NCBI Gene ID

10715

Swiss Prot

P27544

Accession Number

NP_067090.1, NP_937850.1

Host

Goat

Reactivity

Human

Immunogen

The immunogen for this antibody is: C-KDLREYDTAEAQ

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cancer

Purification

Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.

Positive Control

Cat. No. 1366 - Human Frontal Lobe Tissue Lysate

Concentration

500 ug/mL

Homology

Expected Species Reactivity based on sequence homology: Mouse, Pig, Cow

Buffer

Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. Aliquot and store at -20°C. Minimize freezing and thawing.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Aliquot and store at -20˚ C. Minimize freezing and thawing.

Specificity

This antibody is expected to recognize both reported isoforms (NP_067090.1and NP_937850.1) .

Applications Notes

Peptide ELISA: Western Blot:

Symbol

LASS1

NCBI Official Name

Ceramide synthase 1

NCBI Organism

Homo sapiens

Background Reference 01

Venkataraman K, Riebeling C, Bodennec J, Riezman H, Allegood JC, Sullards MC, Merrill AH Jr, Futerman AH. Upstream of growth and differentiation factor 1 (uog1), a mammalian homolog of the yeast longevity assurance gene 1 (LAG1), regulates N-stearoyl-sphinganine (C18- (dihydro) ceramide) synthesis in a fumonisin B1-independent manner in mammalian cells. J Biol Chem. 2002 Sep 20;277 (38) :35642-9. Epub 2002 Jun 24.

Other Product Names

LAG1, CerS1, LASS1, LAG1 homolog, ceramide synthase 1, MGC90349, UOG1, LAG1 longevity assurance homolog 1, longevity assurance (LAG1, S. cerevisiae) homolog 1, longevity assurance gene 1, upstream of GDF1