THRA Antibody

Product Specifications

NCBI Gene ID

7067

Swiss Prot

P10827

Accession Number

NP_955366.1, NP_003241.2

Host

Goat

Reactivity

Human

Immunogen

The immunogen for this antibody is: C-KEEMIRSLQQRP

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cancer

Purification

Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.

Positive Control

Human Bone Marrow Lysate

Concentration

500 ug/mL

Homology

Expected Species Reactivity based on sequence homology: Mouse, Rat, Dog, Pig, Cow

Buffer

Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. Aliquot and store at -20°C. Minimize freezing and thawing.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Aliquot and store at -20˚ C. Minimize freezing and thawing.

Specificity

This antibody is expected to recognize both reported isoforms (NP_955366.1; NP_003241.2) . This antibody is not expected to cross-react to THRB.

Applications Notes

Peptide ELISA: Western Blot:Immunohistochemistry:

Symbol

THRA

NCBI Official Name

Thyroid hormone receptor, alpha

NCBI Organism

Homo sapiens

Background Reference 01

Nishiyama K, Baba S, Yamada T, Matsushita A, Natsume H, Nakano K, Sasaki S, Nakamura H. Embryonic lethal effect of expressing a dominant negative mutant human thyroid hormone receptor alpha1 in mice. Endocr J. 2003 Oct;50 (5) :561-70.

Other Product Names

THRA, thyroid hormone receptor, alpha (erythroblastic leukemia viral (v-erb-a) oncogene homolog, avian), AR7, EAR7, ERB-T-1, ERBA, ERBA1, MGC000261, MGC43240, NR1A1, THRA1, THRA2, c-ERBA-1, ERBA-related 7, avian erythroblastic leukemia viral (v-erb-a) oncogene homolog, thyroid hormone receptor, alpha, triiodothyronine receptor