APH1A Antibody

Product Specifications

NCBI Gene ID

51107

Swiss Prot

Q96BI3

Accession Number

NP_001071096.1, NP_057106.2

Host

Goat

Reactivity

Human

Immunogen

The immunogen for this antibody is: C-HVTDRSDARLQYG

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cancer

Purification

Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.

Positive Control

Cat. No. XBL-10106 - Human Cerebral Cortex Tissue Lysate

Concentration

500 ug/mL

Homology

Expected Species Reactivity based on sequence homology: Mouse, Rat, Dog, Pig, Cow

Buffer

Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. Aliquot and store at -20°C. Minimize freezing and thawing.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Aliquot and store at -20˚ C. Minimize freezing and thawing.

Specificity

This antibody is expected to recognize isoform 1 (NP_001071096.1) and isoform 2 (NP_057106.2) .

Applications Notes

Peptide ELISA: Western Blot:Immunohistochemistry:

Symbol

APH1A

NCBI Official Name

APH1A gamma secretase subunit

NCBI Organism

Homo sapiens

Background Reference 01

Spasic D, Raemaekers T, Dillen K, Declerck I, Baert V, Serneels L, Fullekrug J, Annaert W. Rer1p competes with APH-1 for binding to nicastrin and regulates gamma-secretase complex assembly in the early secretory pathway. J Cell Biol. 2007 Feb 26;176 (5) :629-40.