ACVR1 Antibody

Product Specifications

NCBI Gene ID

Swiss Prot

Q04771

Accession Number

NP_001096.1

Host

Goat

Reactivity

Human

Immunogen

The immunogen for this antibody is: C-RKFKRRNQERLNPRD

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cancer

Purification

Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.

Positive Control

Human Umbilical Cord Lysate

Concentration

500 ug/mL

Homology

Expected Species Reactivity based on sequence homology: Mouse, Rat, Dog

Buffer

Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. Aliquot and store at -20°C. Minimize freezing and thawing.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Aliquot and store at -20˚ C. Minimize freezing and thawing.

Specificity

Reported variants represent identical protein: NP_001096.1, NP_001104537.1

Applications Notes

Peptide ELISA: Western Blot:Immunohistochemistry:

Symbol

ACVR1

NCBI Official Name

Activin A receptor, type I

NCBI Organism

Homo sapiens

Background Reference 01

Shore EM, Xu M, Feldman GJ, Fenstermacher DA, Cho TJ, Choi IH, Connor JM, Delai P, Glaser DL, LeMerrer M, Morhart R, Rogers JG, Smith R, Triffitt JT, Urtizberea JA, Zasloff M, Brown MA, Kaplan FS. A recurrent mutation in the BMP type I receptor ACVR1 causes inherited and sporadic fibrodysplasia ossificans progressiva. Nat Genet. 2006 May;38 (5) :525-7. Epub 2006 Apr 23. Erratum in: Nat Genet. 2007

Other Product Names

ACVR1, activin A receptor, type I, ACTRI, ACVRLK2, ALK2, FOP, SKR1, activin A receptor, type II-like kinase 2, activin A type I receptor, hydroxyalkyl-protein kinase