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POLRMT Antibody

Product Specifications

Background

This gene encodes a mitochondrial DNA-directed RNA polymerase. The gene product is responsible for mitochondrial gene expression as well as for providing RNA primers for initiation of replication of the mitochondrial genome. Although this polypeptide has the same function as the three nuclear DNA-directed RNA polymerases, it is more closely related to RNA polymerases of phage and mitochondrial polymerases of lower eukaryotes.

NCBI Gene ID

5442

Swiss Prot

O00411

Accession Number

NP_005026.3

Host

Goat

Immunogen

The immunogen for this antibody is: C-KETLQAVPKPGAFD

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Signal Transduction

Purification

Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.

Concentration

500 ug/mL

Homology

Expected Species Reactivity based on sequence homology: Human

Buffer

Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. Aliquot and store at -20°C. Minimize freezing and thawing.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Aliquot and store at -20˚ C. Minimize freezing and thawing.

Applications Notes

Peptide ELISA: Western Blot:

Symbol

POLRMT

NCBI Official Name

Polymerase (RNA) mitochondrial (DNA directed)

NCBI Organism

Homo sapiens

Background Reference 01

Ringel R, Sologub M, Morozov YI, Litonin D, Cramer P, Temiakov D.Structure of human mitochondrial RNA polymerase.

Other Product Names

POLRMT, polymerase (RNA) mitochondrial (DNA directed), APOLMT, MTRNAP, MTRPOL, h-mtRPOL, DNA-directed RNA polymerase, mitochondrial

Tested Applications

ELISA

Protein ID

110618253

Physical Properties

Liquid

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