FTO Antibody [FT62-6]
Product Specifications
Background
FTO (Fat mass-and obesity-associated gene) is the responsible gene for mouse ‘fused toes’ mutation. An association between FTO genotype and type 2 diabetes has been confirmed. The presence of the FTO rs9939609 A-allele was found to be positively correlated with other symptoms of the metabolic syndrome, including higher fasting insulin, glucose, triglycerides, and lower HDL-cholesterol.
NCBI Gene ID
26383
Swiss Prot
Q8BGW1
Accession Number
81873739
Host
Mouse
Reactivity
Mouse
Immunogen
Recombinant human FTO.
Clonality
Monoclonal
Clone
FT62-6
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Obesity
Concentration
1 mg/ml
Buffer
Liquid. 0.2um-filtered solution in PBS, pH 7.4. Contains no preservatives.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Stable for at least 1 year after receipt when stored at -20˚ C.
Product Datasheet
https://www.prosci-inc.com/?datasheet_sku=36-084
Fragment
IgG1, kappa
Specificity
Recognizes mouse FTO. Weakly cross-reacts with human FTO. Does not cross-react with rat FTO.
Applications Notes
ELISA: (direct and indirect: 1:2,000-1:5,000) . Immunohistochemistry: (paraffin sections (1:100-1:500) ) . Immunoprecipitation: (5ug/ml per sample in a final reaction volume of 500-1000ul) . Western Blot: (1:2,000-1:5,000 using ECL. Suggested blocking and dilution buffer is PBST containing 0.05% Tween 20 and 5% skim milk. Suggested incubation time is 1 hour at room temperature) . Optimal conditions must be determined individually for each application.
Symbol
Fto
NCBI Official Name
Fat mass and obesity associated
NCBI Organism
Mus musculus
Other Product Names
Fat Mass and Obesity-associated Protein; FATSO
Tested Applications
ELISA, IHC, IP, WB
Protein ID
Q8BGW1
Physical Properties
Liquid
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
