MAN2A1 Antibody

Product Specifications

Background

This gene encodes a protein which is a member of family 38 of the glycosyl hydrolases. The protein is located in the Golgi and catalyzes the final hydrolytic step in the asparagine-linked oligosaccharide (N-glycan) maturation pathway. Mutations in the mouse homolog of this gene have been shown to cause a systemic autoimmune disease similar to human systemic lupus erythematosus.

NCBI Gene ID

4124

Swiss Prot

Q16706

Accession Number

Q16706

Host

Rabbit

Reactivity

Human

Immunogen

This MAN2A1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 456-482 amino acids from the Central region of human MAN2A1.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Obesity, Signal Transduction

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

131 kDa

Fragment

Rabbit Ig

Symbol

MAN2A1

NCBI Official Name

Alpha-mannosidase 2

NCBI Organism

Homo sapiens

Background Reference 01

Han, S., et al. Leuk. Res. 34 (10) :1271-1274 (2010)

Background Reference 02

Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :

Background Reference 03

Zhou, J.B., et al. Med. Sci. Monit. 16 (6), BR179-BR183 (2010) :

Background Reference 04

Miyagawa, H., et al. Rheumatology (Oxford) 47 (2) :158-164 (2008)

Other Product Names

Alpha-mannosidase 2, Golgi alpha-mannosidase II, AMan II, Man II, Mannosidase alpha class 2A member 1, Mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase, MAN2A1, MANA2