ORMDL3 Antibody

Product Specifications

Background

Negative regulator of sphingolipid synthesis. May indirectly regulate endoplasmic reticulum-mediated Ca (+2) signaling.

NCBI Gene ID

94103

Swiss Prot

Q8N138

Accession Number

Q8N138

Host

Rabbit

Reactivity

Human, Mouse

Immunogen

This ORMDL3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 53-81 amino acids from the Central region of human ORMDL3.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Signal Transduction

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Homology

Predicted species reactivity based on immunogen sequence: Rat, Zebrafish, Xenopus, Bovine

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

17 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

ORMDL3

NCBI Official Name

ORM1-like protein 3

NCBI Organism

Homo sapiens

Background Reference 01

Fransen, K., et al. Hum. Mol. Genet. 19 (17) :3482-3488 (2010) Liu, X., et al. Nat. Genet. 42 (8) :658-660 (2010) Halapi, E., et al. Eur. J. Hum. Genet. 18 (8) :902-908 (2010) Dobbins, S.E., et al. Int. J. Cancer (2010) In pressMcGovern, D.P., et al. Nat. Genet. 42 (4) :332-337 (2010)