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HNRNPC Antibody

Product Specifications

Background

This gene belongs to the subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs) . The hnRNPs are RNA binding proteins and they complex with heterogeneous nuclear RNA (hnRNA) . These proteins are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. The protein encoded by this gene can act as a tetramer and is involved in the assembly of 40S hnRNP particles. Multiple transcript variants encoding at least two different isoforms have been described for this gene. [provided by RefSeq].

NCBI Gene ID

3183

Swiss Prot

P07910

Accession Number

P07910

Host

Rabbit

Reactivity

Human

Immunogen

This HNRNPC antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 279-306 amino acids from the C-terminal region of human HNRNPC.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Other

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Homology

Predicted species reactivity based on immunogen sequence: Mouse, Rabbit

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

34 kDa

Fragment

Rabbit Ig

Symbol

HNRNPC

NCBI Official Name

Heterogeneous nuclear ribonucleoproteins C1/C2

NCBI Organism

Homo sapiens

Background Reference 01

Konig, J., et al. Nat. Struct. Mol. Biol. 17 (7) :909-915 (2010)

Background Reference 02

Lee, E.K., et al. Nat. Struct. Mol. Biol. 17 (6) :732-739 (2010)

Background Reference 03

Brunner, J.E., et al. Virology 400 (2) :240-247 (2010)

Background Reference 04

Ertel, K.J., et al. J. Virol. 84 (9) :4229-4242 (2010)

Other Product Names

Heterogeneous nuclear ribonucleoproteins C1/C2, hnRNP C1/C2, HNRNPC, HNRPC

Tested Applications

WB, IHC-P

Protein ID

108935845

Physical Properties

Liquid

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