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BEX1 Antibody

Product Specifications

Background

Signaling adapter molecule involved in p75NTR/NGFR signaling. Plays a role in cell cycle progression and neuronal differentiation. Inhibits neuronal differentiation in response to nerve growth factor (NGF) . May act as a link between the cell cycle and neurotrophic factor signaling, possibly by functioning as an upstream modulator of receptor signaling, coordinating biological responses to external signals with internal cellular states (By similarity) .

NCBI Gene ID

55859

Swiss Prot

Q9HBH7

Accession Number

Q9HBH7

Host

Rabbit

Reactivity

Human

Immunogen

This BEX1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 63-90 amino acids from the Central region of human BEX1.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cancer, Neuroscience, Signal Transduction

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Homology

Predicted species reactivity based on immunogen sequence: Monkey

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

15 kDa

Fragment

Rabbit Ig

Symbol

BEX1

NCBI Official Name

Protein BEX1

NCBI Organism

Homo sapiens

Background Reference 01

Ding, K., et al. Carcinogenesis 30 (1) :35-42 (2009)

Background Reference 02

Foltz, G., et al. Cancer Res. 66 (13) :6665-6674 (2006)

Background Reference 03

Alvarez, E., et al. Gene 357 (1) :18-28 (2005)

Background Reference 04

Quentmeier, H., et al. Leukemia 19 (8) :1488-1489 (2005)

Other Product Names

Protein BEX1, Brain-expressed X-linked protein 1, BEX1

Tested Applications

WB, IHC-P, Flow

Protein ID

91208332

Physical Properties

Liquid

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