SORBS1 Antibody

Product Specifications

Background

Plays a role in tyrosine phosphorylation of CBL by linking CBL to the insulin receptor. Required for insulin-stimulated glucose transport. Involved in formation of actin stress fibers and focal adhesions (By similarity) .

NCBI Gene ID

10580

Swiss Prot

Q9BX66

Accession Number

Q9BX66

Host

Rabbit

Reactivity

Human, Hamster

Immunogen

This SORBS1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 866-892 amino acids from the Central region of human SORBS1.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Signal Transduction

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Homology

Predicted species reactivity based on immunogen sequence: Mouse

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

143 kDa

Fragment

Rabbit Ig

Symbol

SORBS1

NCBI Official Name

Sorbin and SH3 domain-containing protein 1

NCBI Organism

Homo sapiens

Background Reference 01

Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) Joslyn, G., et al. Alcohol. Clin. Exp. Res. 34 (5) :800-812 (2010) Gehmlich, K., et al. Eur. J. Cell Biol. 89 (5) :351-364 (2010) Yamada, Y., et al. Hypertens. Res. 32 (5) :325-331 (2009) Fernow, I., et al. BMC Cell Biol. 10, 80 (2009) :