PPP1R3A Antibody

Product Specifications

Background

The glycogen-associated form of protein phosphatase-1 (PP1) derived from skeletal muscle is a heterodimer composed of a 37-kD catalytic subunit and a 124-kD targeting and regulatory subunit. This gene encodes the regulatory subunit which binds to muscle glycogen with high affinity, thereby enhancing dephosphorylation of glycogen-bound substrates for PP1 such as glycogen synthase and glycogen phosphorylase kinase. [provided by RefSeq].

NCBI Gene ID

5506

Swiss Prot

Q16821

Accession Number

Q16821

Host

Rabbit

Reactivity

Human

Immunogen

This PPP1R3A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 754-782 amino acids from the Central region of human PPP1R3A.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Obesity, Signal Transduction

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Homology

Predicted species reactivity based on immunogen sequence: Rb

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

126 kDa

Fragment

Rabbit Ig

Symbol

PPP1R3A

NCBI Official Name

Protein phosphatase 1 regulatory subunit 3A

NCBI Organism

Homo sapiens

Background Reference 01

Yoshida, T., et al. Int. J. Mol. Med. 24 (2) :233-246 (2009)

Background Reference 02

Yoshida, T., et al. Genomics 93 (3) :221-226 (2009)

Background Reference 03

Gieger, C., et al. PLoS Genet. (11), E1000282 (2008) :

Background Reference 04

Savage, D.B., et al. PLoS Med. (1), E27 (2008) :

Other Product Names

Protein phosphatase 1 regulatory subunit 3A, Protein phosphatase 1 glycogen-associated regulatory subunit, Protein phosphatase type-1 glycogen targeting subunit, RG1, PPP1R3A, PP1G