CD109 Antibody

Product Specifications

Background

CD109 is a member of the alpha2-macroglobulin/complement superfamily. The encoded GPI-linked glycoprotein is found on the cell surface of platelets, activated T-cells, and endothelial cells. The protein binds to and negatively regulates signaling of transforming growth factor beta (TGF-beta) .

NCBI Gene ID

135228

Swiss Prot

Q6YHK3

Accession Number

Q6YHK3

Host

Rabbit

Reactivity

Human, Mouse

Immunogen

This CD109 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 82-109 amino acids from the N-terminal region of human CD109.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Immunology

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

162 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

CD109

NCBI Official Name

CD109 antigen

NCBI Organism

Homo sapiens

Background Reference 01

Nie, Y.M., et al. Transfus Med 20 (6) :376-382 (2010)

Background Reference 02

Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :

Background Reference 03

Hagiwara, S., et al. Oncogene 29 (15) :2181-2191 (2010)

Background Reference 04

Bhatti, F.A., et al. Transfus Med 20 (2) :78-87 (2010)

Other Product Names

CD109 antigen, 150 kDa TGF-beta-1-binding protein, C3 and PZP-like alpha-2-macroglobulin domain-containing protein 7, Platelet-specific Gov antigen, p180, r150, CD109, CD109, CPAMD7