Mouse Dnmt2 Antibody

Product Specifications

Background

MDnmt2 does not appear to be active as a DNA methyltransferase; however, its strong binding to DNA suggests that it may mark specific sequences in the genome by binding to DNA through the specific target-recognizing motif. mDnmt2 is strongly expressed in thymus, testis, and at much lower levels in spleen, lung, brain, heart, kidney, liver, skeletal muscle and embryonic stem cells. This protein belongs to the 5-cystosine methyltransferase family.

NCBI Gene ID

13434

Swiss Prot

O55055

Accession Number

O55055

Host

Rabbit

Reactivity

Human, Mouse

Immunogen

This Mouse Dnmt2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 201-230 amino acids from the N-terminal region of mouse Dnmt2.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Other

Purification

This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

47 kDa

Fragment

Rabbit Ig

Symbol

Trdmt1

NCBI Official Name

TRNA (cytosine (38) -C (5) ) -methyltransferase

NCBI Organism

Mus musculus

Background Reference 01

Yoder, J.A., et al., Hum. Mol. Genet. 7 (2) :279-284 (1998) .

Background Reference 02

Okano, M., et al., Nucleic Acids Res. 26 (11) :2536-2540 (1998) .

Other Product Names

TRNA (cytosine (38) -C (5) ) -methyltransferase, DNA (cytosine-5) -methyltransferase-like protein 2, Dnmt2, DNA methyltransferase homolog MmuIIP, DNA MTase homolog MmuIIP, MMmuIIP, Met-2, Trdmt1, Dnmt2, Met2