CTSA Antibody

Product Specifications

Background

CTSA encodes a glycoprotein which associates with lysosomal enzymes beta-galactosidase and neuraminidase to form a complex of high molecular weight multimers. The formation of this complex provides a protective role for stability and activity. Deficiencies in this gene are linked to multiple forms of galactosialidosis.

NCBI Gene ID

5476

Swiss Prot

P10619

Accession Number

P10619

Host

Rabbit

Reactivity

Human, Mouse

Immunogen

This CTSA antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 18-45 amino acids from the N-terminal region of human CTSA.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Obesity, Signal Transduction

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

54 kDa

Fragment

Rabbit Ig

Symbol

CTSA

NCBI Official Name

Lysosomal protective protein

NCBI Organism

Homo sapiens

Background Reference 01

Reich, M., et al. Immunol. Lett. 128 (2) :143-147 (2010)

Background Reference 02

Bonten, E.J., et al. J. Biol. Chem. 284 (41) :28430-28441 (2009)

Background Reference 03

Ewing, R.M., et al. Mol. Syst. Biol. 3, 89 (2007) :

Background Reference 04

Tatano, Y., et al. J. Med. Invest. 53 (1-2), 103-112 (2006) :

Other Product Names

Lysosomal protective protein, Carboxypeptidase C, Carboxypeptidase L, Cathepsin A, Protective protein cathepsin A, PPCA, Protective protein for beta-galactosidase, Lysosomal protective protein 32 kDa chain, Lysosomal protective protein 20 kDa chain, CTSA, PPGB