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BCMO1 Antibody

Product Specifications

Background

Vitamin A metabolism is important for vital processes such as vision, embryonic development, cell differentiation, and membrane and skin protection. The protein encoded by this gene is a key enzyme in beta-carotene metabolism to vitamin A. It catalyzes the oxidative cleavage of beta, beta-carotene into two retinal molecules.

NCBI Gene ID

53630

Swiss Prot

Q9HAY6

Accession Number

Q9HAY6

Host

Rabbit

Reactivity

Human

Immunogen

This BCMO1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 263-292 amino acids from the Central region of human BCMO1.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Obesity, Signal Transduction

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

63 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

BCO1

NCBI Official Name

Beta, beta-carotene 15,15'-monooxygenase

NCBI Organism

Homo sapiens

Background Reference 01

Lietz, G., et al. Arch. Biochem. Biophys. 502 (1) :8-16 (2010)

Background Reference 02

Kim, Y.S., et al. Biotechnol. Lett. 32 (6) :847-853 (2010)

Background Reference 03

Dastani, Z., et al. Eur. J. Hum. Genet. 18 (3) :342-347 (2010)

Background Reference 04

Perry, J.R., et al. Diabetologia 52 (10) :2117-2121 (2009)

Other Product Names

HGNC:13815

Tested Applications

WB

Protein ID

41688803

Physical Properties

Liquid

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