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ADORA2A Antibody

Product Specifications

Background

ADORA2A is a protein which is one of several receptor subtypes for adenosine. The activity of the encoded protein, a G-protein coupled receptor family member, is mediated by G proteins which activate adenylyl cyclase. This protein is abundant in basal ganglia, vasculature and platelets and it is a major target of caffeine.

NCBI Gene ID

135

Swiss Prot

P29274

Accession Number

P29274

Host

Rabbit

Reactivity

Human

Immunogen

This ADORA2A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 273-301 amino acids from the Central region of human ADORA2A.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cell Cycle, Obesity, Neuroscience, Signal Transduction, Growth Factors

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Homology

Predicted species reactivity based on immunogen sequence: Mouse, Rat

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

45 kDa

Fragment

Rabbit Ig

Symbol

ADORA2A

NCBI Official Name

Adenosine receptor A2a

NCBI Organism

Homo sapiens

Background Reference 01

Buira, S.P., et al. J. Neurochem. 115 (1) :283-295 (2010)

Background Reference 02

Bailey, S.D., et al. Diabetes Care 33 (10) :2250-2253 (2010)

Background Reference 03

Rogers, P.J., et al. Neuropsychopharmacology 35 (9) :1973-1983 (2010)

Background Reference 04

Tebano, M.T., et al. ScientificWorldJournal 10, 1768-1782 (2010) :

Other Product Names

Adenosine receptor A2a, ADORA2A, ADORA2

Tested Applications

WB, IF

Protein ID

543740

Physical Properties

Liquid

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