TXNIP Antibody
Product Specifications
Background
TXNIP (Thioredoxin-interacting protein), also called VDUP1 (Vitamin D3 upregulated protein 1) is a member of the Arrestin family of signal transduction proteins. It is a potent tumor suppressor, blocking tumor growth via blocking cell cycle progression, and reduced expression of TXNIP is found in many tumors. One way TXNIP exerts its tumor suppressive function is by suppressing NF-kB activation, possibly via regulation of the NF-kB subunit p65.
NCBI Gene ID
10628
Swiss Prot
Q9H3M7
Host
Rabbit
Reactivity
Human
Immunogen
A recombinant protein fragment from the N-terminal region of human TXNIP was used as the immunogen for this antibody.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cancer
Purification
Protein A affinity chromatography
Concentration
0.5 mg/mL
Buffer
PBS with 0.1 mg/ml BSA and 0.05% sodium azide
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Aliquot and Store at -20˚ C. Avoid freez-thaw cycles.
Product Datasheet
https://www.prosci-inc.com/?datasheet_sku=33-035
Fragment
IgG
Symbol
TXNIP
NCBI Official Name
Thioredoxin interacting protein
NCBI Organism
Homo sapiens
Other Product Names
Thioredoxin-interacting protein, BMP and activin membrane-bound inhibitor homolog, non-metastatic gene A protein, NMA
Tested Applications
WB
Physical Properties
Liquid
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