GCC2 Antibody

Product Specifications

Background

The protein encoded by this gene is a peripheral membrane protein localized to the trans-Golgi network. It is sensitive to brefeldin A. This encoded protein contains a GRIP domain which is thought to be used in targeting. Alternative splicing results in multiple transcript variants.

NCBI Gene ID

9648

Swiss Prot

Q8IWJ2

Accession Number

Q8IWJ2

Host

Rabbit

Reactivity

Human, Mouse

Immunogen

This GCC2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1581-1609 amino acids from the C-terminal region of human GCC2.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Signal Transduction

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Homology

Predicted species reactivity based on immunogen sequence: Rat

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

196 kDa

Fragment

Rabbit Ig

Symbol

GCC2

NCBI Official Name

GRIP and coiled-coil domain-containing protein 2

NCBI Organism

Homo sapiens

Background Reference 01

Houghton, F.J., et al. Cell 138 (4) :787-794 (2009)

Background Reference 02

Hayes, G.L., et al. Mol. Biol. Cell 20 (1) :209-217 (2009)

Background Reference 03

Burguete, A.S., et al. Cell 132 (2) :286-298 (2008)

Background Reference 04

Efimov, A., et al. Dev. Cell 12 (6) :917-930 (2007)

Other Product Names

GRIP and coiled-coil domain-containing protein 2, 185 kDa Golgi coiled-coil protein, GCC185, CLL-associated antigen KW-11, CTCL tumor antigen se1-1, Ran-binding protein 2-like 4, RanBP2L4, Renal carcinoma antigen NY-REN-53, GCC2, KIAA0336, RANBP2L4