FGF7 Antibody

Product Specifications

Background

The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. This protein is a potent epithelial cell-specific growth factor, whose mitogenic activity is predominantly exhibited in keratinocytes but not in fibroblasts and endothelial cells. Studies of mouse and rat homologs of this gene implicated roles in morphogenesis of epithelium, reepithelialization of wounds, hair development and early lung organogenesis.

NCBI Gene ID

2252

Swiss Prot

P21781

Accession Number

P21781

Host

Rabbit

Reactivity

Human

Immunogen

This FGF7 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 57-86 amino acids from the Central region of human FGF7.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cancer, Cell Cycle, Signal Transduction

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Homology

Predicted species reactivity based on immunogen sequence: Mouse, Rat

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

23 kDa

Fragment

Rabbit Ig

Symbol

FGF7

NCBI Official Name

Fibroblast growth factor 7

NCBI Organism

Homo sapiens

Background Reference 01

Lin, C.B., et al. J. Dermatol. Sci. 59 (2) :91-97 (2010)

Background Reference 02

Bando, M., et al. Immunol. Cell Biol. 88 (3) :328-333 (2010)

Background Reference 03

Wang, X., et al. Biomaterials 31 (9) :2542-2548 (2010)

Background Reference 04

Jugessur, A., et al. PLoS ONE (7), E11493 (2010) :

Other Product Names

Fibroblast growth factor 7, FGF-7, Heparin-binding growth factor 7, HBGF-7, Keratinocyte growth factor, FGF7, KGF

Tested Applications

WB, IHC-P

Protein ID

122756

Physical Properties

Liquid

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