PEX1 Antibody
Product Specifications
Background
This gene encodes a member of the AAA ATPase family, a large group of ATPases associated with diverse cellular activities. This protein is cytoplasmic but is often anchored to a peroxisomal membrane where it forms a heteromeric complex and plays a role in the import of proteins into peroxisomes and peroxisome biogenesis. Mutations in this gene have been associated with complementation group 1 peroxisomal disorders such as neonatal adrenoleukodystrophy, infantile Refsum disease, and Zellweger syndrome.
NCBI Gene ID
5189
Swiss Prot
O43933
Accession Number
O43933
Host
Rabbit
Reactivity
Human
Immunogen
This PEX1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 599-628 amino acids from the Central region of human PEX1.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Signal Transduction
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
143 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
PEX1
NCBI Official Name
Peroxisome biogenesis factor 1
NCBI Organism
Homo sapiens
Background Reference 01
Zhao, J., et al. BMC Med. Genet. 11, 96 (2010) :
Background Reference 02
Yik, W.Y., et al. Hum. Mutat. 30 (3), E467-E480 (2009) :
Background Reference 03
Gudbjartsson, D.F., et al. Nat. Genet. 40 (5) :609-615 (2008)
Background Reference 04
Matsuoka, S., et al. Science 316 (5828) :1160-1166 (2007)
Other Product Names
Peroxisome biogenesis factor 1, Peroxin-1, Peroxisome biogenesis disorder protein 1, PEX1
Tested Applications
WB
Physical Properties
Liquid
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