ABCC10 Antibody

Product Specifications

Background

The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, and White) . This ABC full-transporter is a member of the MRP subfamily which is involved in multi-drug resistance. Multiple transcript variants encoding different isoforms have been found for this gene.

NCBI Gene ID

89845

Swiss Prot

Q5T3U5

Accession Number

Q5T3U5

Host

Rabbit

Reactivity

Human

Immunogen

This ABCC10 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 767-793 amino acids from the Central region of human ABCC10.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cancer, Obesity, Signal Transduction

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

162 kDa

Fragment

Rabbit Ig

Symbol

ABCC10

NCBI Official Name

Multidrug resistance-associated protein 7

NCBI Organism

Homo sapiens

Background Reference 01

Kuang, Y.H., et al. Biochem. Pharmacol. 79 (2) :154-161 (2010)

Background Reference 02

Saito, A., et al. J. Hum. Genet. 54 (6) :317-323 (2009)

Background Reference 03

Zhou, Y., et al. Biochem. Pharmacol. 77 (6) :993-1001 (2009)

Background Reference 04

Hopper-Borge, E., et al. Cancer Res. 69 (1) :178-184 (2009)

Other Product Names

Multidrug resistance-associated protein 7, ATP-binding cassette sub-family C member 10, ABCC10, MRP7, SIMRP7

Tested Applications

WB, IHC-P, Flow

Protein ID

74756298

Physical Properties

Liquid

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